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Immunolab.png

Immunolab GmbH主要从事开发和生产各种免疫诊断试剂,可用于过敏诊断、自身免疫血清学、传染病以及食物分析等领域。在过敏诊断领域,主要产品是一系列综合过敏原的免疫球蛋白IgE、IgG、IgG1和IgG4试剂盒。

 

Founded in 1992, Immunolab started its operations as routine laboratory for allergy diagnostics. The name Immunolab originates from this task, applying immunological methods. Soon we started with the development, production and distribution of our own products. Both, food safety and IVD medical devices were covered from the very beginning. Products and processes were driven by quality thinking which resulted in the accredited establishment of our quality management system in 2002, followed by the accreditation of all IVD products according to the European legislation. As a demand of constant growth we moved to our own facility in 2007, which was extended considerably in 2015 and is equipped according to all modern standards. In 2014 Immunolab joined Biovendor group. This gave us the chance to combine all our experience and flexibility as a smaller-scale company with the opportunities of a larger network of companies.

 

主要产品:

Clinical Diagnostics (human)

Clinical Diagnostics (veterinary)

Food Analytics / Safety

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Life Diagnostics.png

Life Diagnostics公司专注于研发和生产临床前研究以及动物医学诊断相关的ELISA试剂盒、纯化的生物标志物和抗体等产品。产品覆盖心血管疾病、急性期反应、免疫毒性和免疫学标志物等研究领域,主要应用于小鼠、大鼠、兔、猫、狗、猪、猴和鸡等物种。此外,鉴于越来越多的研究围绕聚乙二醇化(PEGylated)生物制剂,Life Diagnostics公司也开发出了抗体PEG单克隆抗体和ELISA试剂盒用于检测PEG以及PEG化的蛋白。

 

Life Diagnostics manufactures ELISA kits, SPARCL™ kits, purified biomarkers and antibodies for preclinical research and veterinary diagnostics. Our areas of expertise include cardiovascular, acute phase, immunotoxicity and immunology biomarkers in species including mouse, rat, rabbit, cat, dog, pig, cow, monkey and chicken. Because of the increasing research into PEGylated biologics we have also developed anti-PEG monoclonal antibodies and ELISA kits for detection of PEG, mPEGylated proteins and anti-PEG antibodies. We manufacture all of the products listed on our website.

 

Life Diagnotics目前可提供用于检测骨骼肌肌钙蛋白-I(troponin-I)、肌红蛋白(myoglobin)、脂肪酸结合蛋白(fatty acid binding protein, FABP)以及肌球蛋白轻链(myosin light chain-1, MLC-1)等代表性标志分子的ELISA试剂盒;主要提供针对检测小鼠、大鼠、兔、狗、猪和猴等种属的检测试剂盒。与肌红蛋白蛋白和心脏型FABP不同,骨骼肌肌钙蛋白I特异性表达于骨骼肌细胞,因此为检测肌肉损伤的首选标志物分子。

 

Life Diagnotics生产的PEG试剂主要包括抗体、ELISA试剂盒以及PE化蛋白。

(1)PEG抗体

(2)PEG ELISA试剂盒:竞争法ELISA检测PEG化蛋白(含甲氧基,或不含甲氧基);夹心法ELISA快速检测甲氧基PEG(mPEG)和mPEG化蛋白;抗PEG IgG和IgM ELISA试剂盒用于检测小鼠、大鼠和猴血清或血浆中PEG抗体的水平。

(3)PEG化蛋白

 

此外,Life Diagnostics还提供PEG包被的微孔板和封闭缓冲液,专门设计用于免疫检测PEG或PEG化抗体。大多数商业化的ELISA试剂盒含有去垢剂如Tween-20(一种含有PEG的去垢剂)会干扰PEG的检测。Life Diagnostics公司提供的封闭缓冲液不含去垢剂和PEG, 可用于稳定包被有PEG或PEG抗体的平板。

 

Life Diagnostics除提供多种心肌标志物ELISA检测试剂盒之外,还生产多种纯化的心肌生物标志物蛋白,包括肌钙蛋白I、肌钙蛋白T、肌钙蛋白复合物、肌红蛋白和脂肪酸结合蛋白等,可提供来自不同物种包括人、小鼠、大鼠、豚鼠、兔、狗、猪、牛和猴的蛋白。

 

主要产品包括:

SPARCL Kits

Acute Phase Rgts. »

Cardiac Biomarkers »

Immunoglobulin Rgts. »

Immunotoxicity ELISA Kits

PEG Reagents »

Skeletal Muscle Rgts. »

Liver Biomarkers

Misc Biomarkers

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Trevigen.jpg

Trevigen致力于为研究人员提供高品质的试剂和试剂盒,用于细胞程序性死亡、DNA损伤和修复的研究。在过去的十年里,对于凋亡的研究越来越多,然而直到最近才开始将凋亡与DNA损伤联系在一起,并给予极大的关注。Trevigen能够为这一新兴领域提供高水平的产品和支持。而基于Trevigen在肿瘤研究产品核心业务的自然延伸,Trevigen开发出了一系列用于研究肿瘤细胞功能和行为的产品,包括血管生成、细胞侵袭、浸润和肿瘤形成等产品和试剂盒。所有Trevigen品牌的产品均基于最高质量标准生产,并被给予最强有力的技术支持。

 

Trevigen, Inc. is an innovative biotechnology company focused on the development of products and technology for cancer research and genetic toxicology, emphasizing apoptosis, DNA damage and repair, and cancer cell function and behavior. The company is located in the I-270 “Technology Corridor” in Gaithersburg, Maryland. Trevigen-brand research products are marketed via the Internet, journal advertising, direct mail, and telemarketing, giving Trevigen worldwide recognition among those in the area of cancer research. Distributor appointments have been made in the Americas, Europe, and the Pacific Rim. Trevigen also has in place supply agreements with major government and university medical research centers in order to make us a part of the growing areas of government research and pharmaceutical research. The company is the recipient of several SBIR grants from the National Institutes of Health, concerning technology development for the analysis of DNA damage.

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exocell.jpgPolysciences LOGO 2.5比1.jpg

艾美捷科技代理Polysciences品牌。

Polysciences的产品以其高质量和多样性而著称,特别是在聚乙烯亚胺(Polyethylenimine,PEI)转染试剂方面有着显著的优势。Polysciences公司成立于1961年,主要生产和经营生命科学(胶体金、不含甲醛的甲醇等)、病理学和显镜学微球和粒子、磁珠、各种单体和聚体等产品;作为世界上最大最全的多聚化合物供应商,同时也是世界领先的免疫学、组织化学试剂耗材供应商。


Polysciences特色的PEI转染试剂特点包括:

(1)高效性:PEI转染试剂具有高效的瞬转效率和蛋白产量,广泛应用于基因和细胞治疗产品的开发,包括病毒载体和蛋白质工艺开发、临床试验以及商业化生产。

(2)广泛适用性:适用于多种细胞系,如HEK293、CHO、Sf9等,且转染效率高达80%~90%。

(3)升级产品:如PEI MAX 40K,作为第一代PEI 25K的升级产品,其去乙酰化和盐酸盐形式增强了水溶性,提高了转染效率。


产品应用范围包括:

病毒载体开发:可用于生产和优化病毒载体,将基因修饰的病毒载体导入目标细胞内,从而实现基因转染;

重组蛋白表达:可以将编码目标蛋白的基因高效地转入宿主细胞,从而大量表达所需的重组蛋白;

基因编辑技术:如CRISPR-Cas9系统中,PEI转染试剂用于将相关基因编辑组件送入细胞内;

细胞治疗研究:用于提高细胞的治疗效果和生存率,需要将特定的遗传物质传递到细胞内,以改变细胞的行为或增强其治疗效果。

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Toronto Research Chemicals.jpg

Toronto Research Chemical建立于1982年,致力于为生物医药研发人员提供小分子有机物,库存超过57000种,并通过一系列方法保证标准物质的纯度。

 

Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.

 

Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.

 

Toronto Research Chemical的产品涵盖:

Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.

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